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Cruises from Santiago area

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Showing 1–30 of 31 sailings

Seabourn Pursuit · South America

10-Day Chilean Fjords

Nov 12 to Nov 22, 2026 · 10 nights

San Antonio (Santiago), Chile to Buenos Aires

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event, The Finale Sail

Ports of call and details

From $5,939 per guest based on double occupancy

Veranda Suite, The Finale Sail

Taxes & fees included

Veranda Suite
$5,939
Penthouse Suite
$12,998
Panorama Penthouse Suite
$13,908
Ocean View
Owner's Suite and Above
Request this sailing

Majestic Princess · South America

Cape Horn & Glaciers of Patagonia

Dec 22, 2026 to Jan 6, 2027 · 15 nights

Santiago (Valparaiso), Chile to Buenos Aires, Argentina

Offers: Last Minute Cruise Deals

Ports of call and details

Save $3,183 · 63% off

From $1,906$5,089 per person, double occupancy

Interior, Last Minute Cruise Deals

+ $553 taxes & fees

Interior
$1,906$5,089
Balcony
$2,102$7,269
Mini-Suite
$2,199$8,209
Suite
$8,107$14,199
Oceanview
Request this sailing

Carnival Firenze · South America

14-Day South America

Jan 19 to Feb 2, 2027 · 14 nights

Valparaiso (Santiago) to Buenos Aires

Ports of call and details

From $1,398 per person, double occupancy

Interior

Taxes & fees included

Interior
$1,398
Ocean View
$2,068
Balcony
$2,478
Suite
Request this sailing

Oceania CruisesOceania Insignia · South America

Southern Fjords & Glaciers: Valparaiso to Buenos Aires

Feb 14 to Mar 7, 2027 · 21 nights

Valparaiso (Santiago) to Buenos Aires, Argentina

  • Specialty coffees, sodas, juices and water
  • Wi-Fi throughout the ship
  • Shipboard gratuities included
  • Specialty restaurants included
  • +1 more

Offers: Your World Included

Ports of call and details

Save $7,949 · 50% off

From $7,949$15,898 per guest, double occupancy; air not included

Inside Stateroom (G)

Inside Stateroom (G)
$7,949$15,898
Ocean View
$8,599$17,198
Vista Suite
$20,299$40,598
Inside Stateroom (F)
Deluxe Ocean View (C1)
Deluxe Ocean View (C2)
Concierge Level Veranda (A1)
Concierge Level Veranda (A2)
Concierge Level Veranda (A3)
Veranda Stateroom (B1)
Veranda Stateroom (B2)
Penthouse Suite (PH1)
Penthouse Suite (PH2)
Penthouse Suite (PH3)
Owner’s Suite
Request this sailing

Oceania CruisesOceania Insignia · South America

Captain Drake's Crossroads: Valparaiso to Rio de Janeiro

Feb 14 to Mar 19, 2027 · 33 nights

Valparaiso (Santiago) to Rio de Janeiro, Brazil

  • Specialty coffees, sodas, juices and water
  • Wi-Fi throughout the ship
  • Shipboard gratuities included
  • Specialty restaurants included
  • +1 more

Offers: Your World Included

Ports of call and details

Save $32,799 · 50% off

From $32,799$65,598 per guest, double occupancy; air not included

Vista Suite

Vista Suite
$32,799$65,598
Inside Stateroom (F)
Inside Stateroom (G)
Deluxe Ocean View (C1)
Deluxe Ocean View (C2)
Ocean View
Concierge Level Veranda (A1)
Concierge Level Veranda (A2)
Concierge Level Veranda (A3)
Veranda Stateroom (B1)
Veranda Stateroom (B2)
Penthouse Suite (PH1)
Penthouse Suite (PH2)
Penthouse Suite (PH3)
Owner’s Suite
Request this sailing

Oosterdam · South America

14-Day South America Pathways: Chilean Fjords & Glaciers

Feb 23 to Mar 9, 2027 · 14 nights

San Antonio (Santiago), Chile to Buenos Aires, Argentina

  • Drink package
  • Wi-Fi
  • Specialty dining
  • Shore excursions

Offers: Have It All - Our Premium Cruise Package

Ports of call and details

From $3,649 per person, double occupancy

Inside, Have It All - Our Premium Cruise Package

Taxes & fees included

Inside
$3,649
Ocean View
$3,749
Verandah
$5,299
Request this sailing

Queen Anne · South America

Valparaiso To Fort Lauderdale

Feb 28 to Mar 19, 2027 · 19 nights

Valparaiso (tours to Santiago), Chile to Fort Lauderdale, Florida, USA

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Fall Savings Event, 2026 Black Friday Event

Ports of call and details

From $2,699 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$2,699
Britannia Oceanview
$3,539
Britannia Balcony
$3,799
Britannia Club Balcony
$6,039
Princess Grill Suite
$8,999
Queens Grill Suite
$16,559
Request this sailing

Queen Anne · South America

Valparaiso To Southampton

Feb 28 to Apr 2, 2027 · 33 nights

Valparaiso (tours to Santiago), Chile to Southampton, England

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Sailing Soon Savings, Fall Savings Event, 2026 Black Friday Event

Ports of call and details

From $4,349 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$4,349
Britannia Oceanview
$6,489
Britannia Balcony
$6,789
Britannia Club Balcony
$9,669
Princess Grill Suite
$15,969
Queens Grill Suite
$23,349
Request this sailing

Queen Anne · South America

Valparaiso To Hamburg

Feb 28 to Apr 5, 2027 · 36 nights

Valparaiso (tours to Santiago), Chile to Hamburg, Germany

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Fall Savings Event, 2026 Black Friday Event

Ports of call and details

From $5,299 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$5,299
Britannia Oceanview
$7,329
Britannia Balcony
$7,989
Britannia Club Balcony
$10,749
Princess Grill Suite
$17,799
Queens Grill Suite
$25,089
Request this sailing

Oosterdam · Panama Canal

16-Day Inca & Panama Canal Discovery: Lima Overnight

Mar 24 to Apr 9, 2027 · 16 nights

San Antonio (Santiago), Chile to Fort Lauderdale, Florida, US

  • Drink package
  • Wi-Fi
  • Specialty dining
  • Shore excursions

Offers: Have It All - Our Premium Cruise Package

Ports of call and details

From $3,339 per person, double occupancy

Inside, Have It All - Our Premium Cruise Package

Taxes & fees included

Inside
$3,339
Ocean View
$3,539
Verandah
$5,039
Signature Suite
$5,839
Neptune Suite
$14,364
Request this sailing

Seabourn Pursuit · South America

19-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers

Apr 7 to Apr 26, 2027 · 19 nights

San Antonio (Santiago), Chile to Papeete, French Polynesia

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event

Ports of call and details

From $17,298 per guest based on double occupancy

Veranda Suite, Explore Beyond Event

Taxes & fees included

Veranda Suite
$17,298
Penthouse Suite
$25,998
Panorama Penthouse Suite
$27,818
Owner's Suite and Above
$50,738
Request this sailing

Seabourn Pursuit · South America

18-Day Chilean Fjords & Antarctica

Oct 18 to Nov 5, 2027 · 18 nights

San Antonio (Santiago), Chile to Buenos Aires

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event

Ports of call and details

From $21,498 per guest based on double occupancy

Veranda Suite, Explore Beyond Event

Taxes & fees included

Veranda Suite
$21,498
Penthouse Suite
$27,998
Panorama Penthouse Suite
$29,958
Owner's Suite and Above
$35,998
Request this sailing

Nieuw Amsterdam · South America

15-Day South America Pathways: Chilean Fjords & Glaciers

Nov 2 to Nov 17, 2027 · 15 nights

San Antonio (Santiago), Chile to Buenos Aires, Argentina

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $3,274 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$3,274
Ocean View
$3,474
Verandah
$4,274
Signature Suite
$5,774
Neptune Suite
$7,174
Request this sailing

Nieuw Amsterdam · South America

15-Day South America Pathways: Chilean Fjords & Glaciers

Dec 2 to Dec 17, 2027 · 15 nights

San Antonio (Santiago), Chile to Buenos Aires, Argentina

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $2,974 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$2,974
Ocean View
$3,174
Verandah
$3,974
Signature Suite
$5,674
Neptune Suite
$6,874
Request this sailing

Nieuw Amsterdam · South America

37-Day South America Pathways & Antarctica Holiday

Dec 2, 2027 to Jan 8, 2028 · 37 nights

Round trip from San Antonio (Santiago), Chile

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus, Holiday Cruises

Ports of call and details

Save $2,590 · 29% off

From $6,449$9,039 per person, double occupancy

Inside, Holiday Cruises

Taxes & fees included

Inside
$6,449$9,039
Ocean View
$6,759$9,349
Verandah
$8,699$11,289
Signature Suite
$12,159$14,749
Neptune Suite
$17,379$19,969
Request this sailing

Majestic Princess · South America

Cape Horn & Glaciers of Patagonia

Dec 6 to Dec 21, 2027 · 15 nights

San Antonio (for Santiago), Chile to Buenos Aires, Argentina

Offers: Fall Savings Sale - Up to 45% Off

Ports of call and details

Save $2,311 · 59% off

From $1,639$3,950 per person, double occupancy

Interior, Fall Savings Sale - Up to 45% Off

+ $600 taxes & fees

Interior
$1,639$3,950
Balcony
$2,082$6,035
Mini-Suite
$2,574$7,425
Suite
$7,474$13,455
Oceanview
Request this sailing

Norwegian Star · South America

Santiago Cruisetour

Dec 30, 2027 to Jan 17, 2028 · 18 nights

Santiago (San Antonio), Chile to Buenos Aires, Argentina

  • Unlimited open bar
  • 150 minutes of Wi-Fi
  • 4 specialty meals
  • $50 off every shore excursion
Ports of call and details

From $3,968 per person, double occupancy, cruise and land package

Inside (cruisetour package)

+ taxes & fees

Inside (cruisetour package)
$3,968
Oceanview (cruisetour package)
$4,268
Balcony (cruisetour package)
$6,168
Club Balcony Suite (cruisetour package)
$6,918
Suite (cruisetour package)
$8,818
The Haven (cruisetour package)
Request this sailing

Norwegian Star · South America

15-Day South America from Santiago to Buenos Aires: Argentina & Chile

Jan 2 to Jan 17, 2028 · 15 nights

Santiago (San Antonio), Chile to Buenos Aires, Argentina

  • Unlimited open bar
  • 150 minutes of Wi-Fi
  • 4 specialty meals
  • $50 off every shore excursion
Ports of call and details

From $3,139 per person, double occupancy

Inside

+ taxes & fees

Inside
$3,139
Oceanview
$3,439
Balcony
$5,339
Club Balcony Suite
$6,089
Suite
$7,989
The Haven
Request this sailing

Nieuw Amsterdam · South America

22-Day South America & Antarctica

Jan 8 to Jan 30, 2028 · 22 nights

San Antonio (Santiago), Chile to Buenos Aires, Argentina

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $7,009 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$7,009
Ocean View
$7,209
Verandah
$10,009
Signature Suite
$13,009
Neptune Suite
$16,109
Request this sailing

Norwegian Star · South America

Santiago Cruisetour

Jan 29 to Feb 16, 2028 · 18 nights

Santiago (San Antonio), Chile to Buenos Aires, Argentina

  • Unlimited open bar
  • 150 minutes of Wi-Fi
  • 4 specialty meals
  • $50 off every shore excursion
Ports of call and details

From $4,258 per person, double occupancy, cruise and land package

Inside (cruisetour package)

+ taxes & fees

Inside (cruisetour package)
$4,258
Oceanview (cruisetour package)
$4,618
Balcony (cruisetour package)
$7,968
Club Balcony Suite (cruisetour package)
$8,218
Suite (cruisetour package)
$8,578
The Haven (cruisetour package)
Request this sailing

Norwegian Star · South America

15-Day South America from Santiago to Buenos Aires: Argentina & Chile

Feb 1 to Feb 16, 2028 · 15 nights

Santiago (San Antonio), Chile to Buenos Aires, Argentina

  • Unlimited open bar
  • 150 minutes of Wi-Fi
  • 4 specialty meals
  • $50 off every shore excursion
Ports of call and details

From $3,429 per person, double occupancy

Inside

+ taxes & fees

Inside
$3,429
Oceanview
$3,789
Balcony
$7,139
Club Balcony Suite
$7,389
Suite
$7,749
The Haven
Request this sailing

Seabourn Quest · South America

28-Day Chilean Fjords, Antarctica & Falklands

Feb 5 to Mar 4, 2028 · 28 nights

Valparaiso (Santiago), Chile to Buenos Aires, Argentina

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event

Ports of call and details

From $19,998 per guest based on double occupancy

Ocean View, Explore Beyond Event

Taxes & fees included

Ocean View
$19,998
Veranda Suite
$26,623
Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Quest · South America

53-Day Chilean Fjords, Antarctica & South Atlantic Explorer

Feb 5 to Mar 29, 2028 · 53 nights

Valparaiso (Santiago), Chile to Cape Town, South Africa

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $34,598 per guest based on double occupancy

Ocean View, Seabourn Combo Savings

Taxes & fees included

Ocean View
$34,598
Veranda Suite
$42,598
Penthouse Suite
Owner's Suite and Above
Request this sailing

Volendam · World/Grand Voyage

46-Day Grand World Voyage

Feb 10 to Mar 28, 2028 · 46 nights

San Antonio (Santiago), Chile to Singapore

  • Up to $2,500 onboard credit
  • Crew appreciation
  • One complimentary shore excursion

Offers: 2028 Grand Voyage Early Booking Benefits

Ports of call and details

From $12,069 per person, double occupancy

Inside, 2028 Grand Voyage Early Booking Benefits

Taxes & fees included

Inside
$12,069
Ocean View
$13,219
Request this sailing

Nieuw Amsterdam · South America

14-Day South America Pathways: Chilean Fjords & Glaciers

Feb 21 to Mar 6, 2028 · 14 nights

San Antonio (Santiago), Chile to Buenos Aires, Argentina

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $3,419 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$3,419
Ocean View
$3,669
Verandah
$4,819
Signature Suite
$6,019
Neptune Suite
$7,819
Request this sailing

Norwegian Star · South America

Santiago Cruisetour

Feb 28 to Mar 17, 2028 · 18 nights

Santiago (San Antonio), Chile to Buenos Aires, Argentina

  • Unlimited open bar
  • 150 minutes of Wi-Fi
  • 4 specialty meals
  • $50 off every shore excursion
Ports of call and details

From $4,268 per person, double occupancy, cruise and land package

Inside (cruisetour package)

+ taxes & fees

Inside (cruisetour package)
$4,268
Oceanview (cruisetour package)
$4,718
Balcony (cruisetour package)
$7,118
Club Balcony Suite (cruisetour package)
$7,568
Suite (cruisetour package)
$9,418
The Haven (cruisetour package)
Request this sailing

Norwegian Star · South America

15-Day South America from Santiago to Buenos Aires: Argentina & Chile

Mar 2 to Mar 17, 2028 · 15 nights

Santiago (San Antonio), Chile to Buenos Aires, Argentina

  • Unlimited open bar
  • 150 minutes of Wi-Fi
  • 4 specialty meals
  • $50 off every shore excursion
Ports of call and details

From $3,439 per person, double occupancy

Inside

+ taxes & fees

Inside
$3,439
Oceanview
$3,889
Balcony
$6,289
Club Balcony Suite
$6,739
Suite
$8,589
The Haven
Request this sailing

Nieuw Amsterdam · Panama Canal

17-Day Inca & Panama Canal Discovery: Lima Overnight

Mar 21 to Apr 7, 2028 · 17 nights

San Antonio (Santiago), Chile to Fort Lauderdale, Florida, US

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $4,084 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$4,084
Ocean View
$4,284
Verandah
$5,184
Signature Suite
$7,384
Neptune Suite
$9,884
Request this sailing

Seabourn Pursuit · South America

22-Day Juan Fernandez Islands, Chilean Fjords & Antarctica

Oct 18 to Nov 9, 2028 · 22 nights

Valparaiso (Santiago), Chile to Buenos Aires

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event, Ruby Collection

Ports of call and details

From $28,898 per guest based on double occupancy

Veranda Suite, Explore Beyond Event

Taxes & fees included

Veranda Suite
$28,898
Penthouse Suite
$42,998
Panorama Penthouse Suite
$46,008
Owner's Suite and Above
$65,998
Request this sailing

Regent Seven Seas CruisesSeven Seas Mariner · South America

The Poets' Passage: Valparaiso to Lima (Callao)

Feb 18 to Feb 26, 2029 · 8 nights

Valparaiso (Santiago) to Lima, Perú

  • Unlimited beverages, fine wines and cocktails
  • Unlimited Wi-Fi
  • Pre-paid gratuities
  • All specialty restaurants included
  • +1 more

Offers: Bonus Savings of up to $2,500 per person

Ports of call and details

Save $12,099 · 63% off

From $7,099$19,198 per person, double occupancy, all-inclusive fare; air not included

Deluxe Veranda Suite G

Deluxe Veranda Suite G
$7,099$19,198
Deluxe Veranda Suite F
$7,399$19,798
Concierge Suite E
$7,799$20,598
Concierge Suite D
$7,999$20,998
Penthouse Suite B
$12,499$29,998
Penthouse Suite A
$12,599$30,198
Deluxe Veranda Suite H
Signature Suite SG
Penthouse Suite C
Horizon View Suite HS
Seven Seas Suite Aft
Seven Seas Suite Forward
Mariner Suite MN
Grand Suite GS
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Fares are per person, double occupancy.